Senior PET Radiochemist/Adjunct Professor and Associate Professor in Chemistry (Radiopharmaceutical chemistry)

NorPET is a consortium consisting of SAFE, IMB and the Norwegian Medical Cyclotron Centre AS, with the aim of promoting and coordinating radiopharmaceutical research across the institutions. NorPET was established to consolidate the PET-tracer development from the selection and synthesis of clinically relevant candidate molecules through pre-clinical studies and all the way to administration to man. Across the three institutions, NorPET provides state of the art PET infrastructure ranging from two cyclotrons, an animal PET-scanner, several commercial and research synthesizer modules, a full suite of QC equipments, GLP, GMP and research laboratories.

The Norwegian Medical Cyclotron Centre AS (NMCC) is the leading PET radiopharmaceutical facility of Norway. The facility opened officially in 2006. NMCC is a non-profit organisation located at Rikshospitalet in Oslo and is part of a national cluster of PET centres. The NMCC AS is owned by three public shareholders; the Oslo University Hospital, Akershus University Hospital, and the University of Oslo. NMCC has produced radionuclides since 2006, but has recently been granted a manufacturing licence for [18F]-NaF and will, in collaboration with SAFE and IMB, focus on the development of commercial tracers and tracers intended for research purposes.

SAFE (Centre for accelerator based research) is located at the Department of Chemistry, University of Oslo. The Department of Chemistry is Norway’s largest department for chemical sciences. The department conducts research at a high international level and teaches at BSc, MSc and PhD levels in all major areas of chemistry. It comprises 2 sections (Life Sciences and Functional Materials) with seven research groups as well as a school laboratory. The staff consist of 36 professors and associate professors, 12 adjunct professors, ca. 45 post.docs and researchers, ca. 65 PhD student. The Accelerator- facilities at the Department of Chemistry consist of a modern hot-cell laboratory of GMP-standard in a refurnished and spacious part of the Chemistry-building. The research group routinely uses the local Oslo Cyclotron to produce positron emitting (and gamma emitting) radionuclides. The cyclotron also facilitates the possibility for production of unusual nuclides with PET-potential, e.g. 64Cu and 62Zn.

IMB (Institute of Basic Medical Sciences), University of Oslo, is the leading research institution for basic medical sciences in Norway. Major research areas include neuroscience, nutrition, cell- and molecular biology, immunobiology, systems physiology, behavioural sciences and biostatistics and biomodeling. The institute is responsible for a large part of the medical curriculum and for the full education of nutrional physiologists. Staff include 55 professors/associate professors, more than 100 post docs and researchers and 130 PhD students. The Institute has a range of laboratories providing relevant complentary techniques for NorPET research and houses several advanced imaging facilities, including a marketed small animal PET/CT unit and testing of prototype PET-scanners developed at the Department of Physics (COMPET).

Senior PET Radiochemist/Adjunct Professor

NMCC AS seeks to recruit an outstanding senior Radiochemist to coordinate the stages of PET-tracer development in NorPET, from the selection and synthesis of clinically relevant candidate molecules to the day-to-day manufacturing of PET-tracers for research purposes and hand over of marketed PET-tracers to the supply chain.

The successful candidate should demonstrate a strong motivation to work in the multidisciplinary and collaborative environment of NorPET reaching out to both applied chemistry, pre-clinical and clinical research groups involved in the PET research community both nationally and internationally.

The successful candidate must hold a Ph.D. or equivalent degree in chemistry or radiochemistry and have a proven track record in the area of PET-chemistry.

The successful candidate must be able to demonstrate a good understanding of all requirements related to development of drug products to be developed, manufactured and administrated in accordance with cGMP and GLP.

Responsibilities:

Establish a cross functional centre of excellence for the development of PET tracers under the NorPET umbrella
Develop a PET-tracer portfolio for NMCC based on clinical relevance and priorities set out by the board
Responsible for planning and manufacturing of research tracers for clinical trials etc.
Documentation of new and existing tracers in accordance with requirements laid out by the Norwegian Medicines Agency
Supervision of Ph.D. students and Master students

An attractive compensation and benefits package will be on offer to the successful candidate.

For further information, please contact Thor Audun Saga, Phone:+47 93 04 78 13 or via e-mail: thor.audun.saga@petsenteret.no

Please forward current CV with academic and professional records to thor.audun.saga@petsenteret.no

Associate professor in chemistry (radiopharmaceutical chemistry) at the Department of Chemistry

Job description

The successful candidate will be a part of the research group for nuclear chemistry which at present consists of two professors, one senior engineer and one radiation safety engineer. The person we are recruiting is expected to build up and lead a research program in radiopharmaceutical chemistry, particularly focused on PET. The successful candidate is expected to work within the multi-disciplinary NorPET-setting involving groups in related fields; e.g. physics, preclinical medicine and relevant clinical groups.

The scientific responsibilities of the position will be to invent, design, synthesize and optimize the chemistry of radiophamaceutical compounds, in particular for PET, and to outline strategies for the PET- activities which are at the state-of-the-art of the field internationally. Supervision of students and organization of projects will be an important part of the work. The successful applicant must be prepared to teach course(s) in chemistry at all levels including radiochemistry at bachelor level as well as advanced courses in the field of speciality.

Normally, 50% of the working time will be devoted to research, research-related activities and research administration. 50 % of the working time will be devoted to teaching, teaching-related activities and administration.

Qualifications

Qualification requirements include a doctoral degree in radiochemistry, organic chemistry or medicinal chemistry and documented experience both in radiochemistry and organic synthesis. Documented experience with PET chemistry is given preference. Qualifications in other fields of radiophamaceutical chemistry e.g. SPECT and targeted radiotherapy will also be acknowledged.

The basis for assessment will be the scholarly production of the applicant, other qualifications, pedagogical or educational, the applicant’s qualifications within leadership and administration as well as the general personal suitability. Demonstrated ability to work within multidisciplinary research groups, as well as experience from initiation of research networks and general network building will be valued. In ranking the competent applicants, the full range of qualifications will be considered and explicitly assessed. In the assessment of the applicants, academic qualifications will be ascribed more weight than other professional qualifications.

On the appointment of a candidate who is not fluent in Norwegian, Swedish or Danish, the appointee will be expected to acquire an adequate level of spoken and written Norwegian to be able to participate actively in all functions the position may involve.

Applicants, who at the time of appointment cannot provide documentary evidence of basic teaching competence, must acquire such competence during a period of two years.

Interviews and trial lectures may be used as part of the appointment process. Reference is otherwise made to rules regarding the procedures for appointment of persons to positions as professors and associate professors at the University of Oslo: http://www.admin.uio.no/admhb/reglhb/personal/tilsettingvitenskapelig/rulesappointprofessor-backup-20080314.xml

and Rules for the assessment and weighting of pedagogical competence for appointments to permanent academic posts which include teaching duties:

http://www.uio.no/admhb/reglhb/personal/tilsettingvitenskapelig/rulesassessmentweight.xml.

Pay grade: 57 – 76 , ( post code 1011, NOK 455 900 - 654 600 depending on qualifications)

Application must include:

Application letter
CV and attachments
Up to 10 selected scientific publications the applicant wishes to include in the evaluation
List of scientific production with bibliographic references
A portfolio containing documentation of teaching experience, capability of external fund raising and other qualifications the applicant wants to have considered
A research plan describing the applicant’s scientific ambitions for the position

Application with CV, application letter, list of publications and any other attachments that one wishes to enclose, must be sent through the University of Oslo's recruitment system, Easycruit.

If problem attaching the requested documents, please send them on e-mail by closing date of application to: t.s.guttormsen@mn.uio.no

In accordance with the University of Oslo`s equal oppotunities policy, we invite applications from all interested individuals regardless of gender or ethnicity.

The University of Oslo has a contract for all employees regarding acquisition of intellectual property rights.